SNSF Consolidator Grant awarded to Prof. Aleksandra Radenovic
© 2015 Prof. Radenovic
Prof. Aleksandra Radenovic has been awarded a CONSOLIDATOR GRANT by the SNSF in the context of the so-called “Temporary Backup Schemes” for the European Research Council (ERC) grants. This transitional measure of the SNSF offers the awardee an adequate substitute for ERC grants.
-
BIONIC - Viscosity gradient in 2D material nanopores as a new playground for biophysics
The main objective of this research proposal is take advantage of recently discovered viscosity gradient system based on room-temperature ionic liquids (RTILs) that permits to discriminate single nucleotides in atomically thin molybdenum disulfide (MoS2) nanopores. We first aim to gain insight into the retardation mechanism; in turn this will help us in selecting the most appropriate RTIL and material for 2D membrane.
To deliver high-throughput technique, we will capitalize on our experience in implementing transverse detection on nanopore platform. Moreover, we recognize that provided solution is passive in its nature and doesn’t allow for active regulation of translocation speed, therefore we plan to implement different means of feedback to fine-tune the RTILs viscosity and the two supplementary methods that can both modulate the nanopore charges.
Finally, by using viscosity gradient platform, we could also examine new physics in confined spaces.
Duration of the project: 60 months
Total Amount: CHF 1’998’728.-
Domains: Mathematics, Natural Sciences, Engineering Sciences, Physics